Little Known Facts About ceesdekker.
Little Known Facts About ceesdekker.
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Rotary movement of DNA rotors on nanopores. Prime row: raw online video in the Cy5 channel of each and every rotor. Middle row: corresponding single-particle localization success of equally ends of your DNA rotors. The situation of the current body is marked as orange and blue dots, and also the trajectory of The ten frames just before The existing frame is revealed as sound strains.
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Throughout the exact same time, the team of Paul McEuen, who was then based mostly in the College of California, Berkeley, showed similar effects on ropes of bundled nanotubes. Dependant upon the wrapping angle, nanotubes can are available in metallic or semiconducting variants, a prediction that we and Charles Lieber’s team at Harvard University independently confirmed working with scanning tunnelling spectroscopy experiments.
Because 2000, Dekker has shifted the principle focus of his perform toward biophysics where he scientific studies the Houses of one biomolecules and cells using the resources of nanotechnology. This modification of industry was driven by his fascination for your impressive performing of Organic molecular structures, in addition to with the very long-term standpoint that many fascinating discoveries might be predicted With this industry.[five] Current lines of study in his biophysics group are inside the areas of:[6]
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and to start with ever study with the dynamics DNA supercoils and the discovery of supercoil hopping
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes
‘At first we looked at biological devices with a Bodily watch and acted on The premise from the equipment we realized. It took a few years ahead of we begun Operating a lot more on the large Organic challenges. I then began to contact it nanobiology, a phrase that did not exist at enough time.
2011, first in vitro measurements of transportation throughout one biomimetic nuclear pore advanced; progress of multiplexed magnetic tweezers for kilo-molecule experiments; and solved the mechanism of homology recognition in DNA homologous recombination
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Resolving the move sizing in condensin-pushed DNA loop extrusion identifies ATP cees dekker binding given that the move-building course of action
FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division
Afterwards we spoke once again briefly mainly because Dekker felt that our dialogue of his religion rapidly grew to become purely philosophical, While What's more, it concretely helps him in his perform.
Permit’s 1st glance back again in the meanwhile whenever you made a decision to change your target from superconductivity and nanotubes to biology at the conclusion of the nineties.
Supercoiling-dependent DNA binding: quantitative modeling and programs to bulk and single-molecule experiments